| Name | Character | Episodes |
|---|---|---|
| Candice Bergen | Murphy Brown | 13 |
| Jake McDorman | Avery Brown | 13 |
| Tyne Daly | Phyllis | 13 |
| Grant Shaud | Miles Silverberg | 13 |
| Joe Regalbuto | Frank Fontana | 13 |
| Faith Ford | Corky Sherwood | 13 |
| Nik Dodani | Pat Patel | 13 |
| Charles Kimbrough | Jim Dial | 3 |
| Hillary Clinton | Hillary | 1 |
| Ashley Austin Morris | Addie | 1 |