| Name | Character | Episodes |
|---|---|---|
| Matt Damon | Mark Watney | 6 |
| Jessica Chastain | Melissa Lewis | 6 |
| Kate Mara | Beth Johanssen | 6 |
| Sebastian Stan | Chris Beck | 6 |
| Sean Bean | Mitch Henderson | 6 |
| Chiwetel Ejiofor | Vincent Kapoor | 6 |
| Kristen Wiig | Annie Montrose | 6 |
| Michael Peña | Rick Martinez | 6 |
| Jeff Daniels | Teddy Sanders | 6 |
| Aksel Hennie | Alex Vogel | 6 |