| Name | Character | Episodes |
|---|---|---|
| Barack Obama | Self (archive footage) | 4 |
| Joe Biden | Self (archive footage) | 3 |
| Donald Trump | Self (archive footage) | 2 |
| Maria Bello | Narrator (voice) | 2 |
| Samira Wiley | Narrator (voice) | 2 |
| Vladimir Putin | Self (archive footage) | 2 |
| Richard Nixon | Self (archive footage) | 2 |
| George H. W. Bush | Self (archive footage) | 2 |
| Lyndon B. Johnson | Self (archive footage) | 2 |
| Jake Gyllenhaal | Narrator (voice) | 1 |
| J.K. Simmons | Narrator (voice) | 1 |
| Rachel McAdams | Narrator (voice) | 1 |
| Joseph Gordon-Levitt | Narrator (voice) | 1 |
| Keke Palmer | Narrator (voice) | 1 |
| Christian Slater | Narrator (voice) | 1 |
| Ethan Hawke | Narrator (voice) | 1 |
| Kristen Bell | Narrator (voice) | 1 |
| Connie Britton | Narrator (voice) | 1 |
| Hector Elizondo | Narrator (voice) | 1 |
| V | Self (archive footage) | 1 |
| Sophie Okonedo | Narrator (voice) | 1 |
| Hilary Swank | Narrator (voice) | 1 |
| Rosario Dawson | Narrator (voice) | 1 |
| Natasha Lyonne | Narrator (voice) | 1 |
| Kyle MacLachlan | Narrator (voice) | 1 |
| Nick Kroll | Narrator (voice) | 1 |
| Maggie Siff | Narrator (voice) | 1 |
| Kim Cattrall | Narrator (voice) | 1 |
| Rainn Wilson | Narrator (voice) | 1 |
| Michael Jordan | Self (archive footage) | 1 |
| Moon Jae-in | Self (archive footage) | 1 |
| Malcolm X | Self (archive footage) | 1 |
| Michelle Obama | Self - First Black First Lady (archive footage) | 1 |
| John Waters | Narrator (voice) | 1 |
| Aasif Mandvi | Narrator (voice) | 1 |
| Jin | Self (archive footage) | 1 |
| Kevin Smith | Narrator (voice) | 1 |
| Keri Russell | Narrator (voice) | 1 |
| LaKeith Stanfield | Narrator (voice) | 1 |
| Catherine Oxenberg | Self - Mother of NXIVM Cult Member | 1 |
| Aya Cash | Narrator (voice) | 1 |
| Ronald Reagan | Self (archive footage) | 1 |
| Anderson Cooper | Self (archive footage) | 1 |
| Jimin | Self (archive footage) | 1 |
| Mark Zuckerberg | Self (archive footage) | 1 |
| Vincent Kartheiser | Narrator (voice) | 1 |
| Adolf Hitler | Self (archive footage) | 1 |
| LeVar Burton | Narrator (voice) | 1 |
| Jerry Springer | Narrator (voice) | 1 |
| Kelly Rowland | Narrator (voice) | 1 |
| Gigi Hadid | Self (archive footage) | 1 |
| Bill Clinton | Self (archive footage) | 1 |
| Muhammad Ali | Self (archive footage) | 1 |
| Jay-Z | Self (archive footage) | 1 |
| Jay-Z | Self (voice) | 1 |
| James Baldwin | Self (archive footage) | 1 |
| Hillary Clinton | Self | 1 |
| Mark Cuban | Self | 1 |
| Fidel Castro | Self (archive footage) | 1 |
| Jesse Jackson | Self (archive footage) | 1 |
| Jane Fonda | Self (archive footage) | 1 |
| Cory Booker | Self - U.S. Senator | 1 |
| RM | Self (archive footage) | 1 |
| Elizabeth Warren | Self (archive footage) | 1 |
| Stephen Colbert | Self (archive footage) | 1 |
| Noam Chomsky | Self (archive footage) | 1 |
| Bill Gates | Self | 1 |
| Ruth Negga | Narrator (voice) | 1 |
| Yara Shahidi | Narrator (voice) | 1 |
| George W. Bush | Self (archive footage) | 1 |
| Doja Cat | Self (archive footage) | 1 |
| Justin Trudeau | Self (archive footage) | 1 |
| Carly Rae Jepsen | Narrator (voice) | 1 |
| Martin Luther King Jr. | Self (archive footage) | 1 |
| Jung Kook | Self (archive footage) | 1 |
| Rachel Bloom | Narrator (voice) | 1 |
| j-hope | Self (archive footage) | 1 |
| Hattie McDaniel | Self - First Black Oscar Winner (archive footage) | 1 |
| Michael Bloomberg | Self (archive footage) | 1 |
| Bernie Sanders | Self | 1 |
| Ted Cruz | Self (archive footage) | 1 |
| Xi Jinping | Self (archive footage) | 1 |
| Big Boi | Self (archive footage) | 1 |
| SUGA | Self (archive footage) | 1 |
| Warren Buffett | Self (archive footage) | 1 |
| Nelson Mandela | Self (archive footage) | 1 |
| Alan Greenspan | Self (archive footage) | 1 |
| Psy | Self (archive footage) | 1 |
| Mike Wallace | Self (archive footage) | 1 |
| Colin Powell | Self - First Black Secretary of State (archive footage) | 1 |
| Boris Johnson | Self (archive footage) | 1 |
| Tom Brokaw | Self (archive footage) | 1 |
| Jesse Owens | Self - Four-Time Olympic Gold Medalist (archive footage) | 1 |
| Park Chung-hee | Self (archive footage) | 1 |
| Jackie Robinson | Self - First Black MLB Player (archive footage) | 1 |
| Jim Jones | Self (archive footage) | 1 |
| Ta-Nehisi Coates | Self (archive footage) | 1 |
| John D. Rockefeller | Self (archive footage) | 1 |
| Kim Dae-jung | Self (archive footage) | 1 |