| Name | Character | Episodes |
|---|---|---|
| Fiona Shaw | Marla Painter | 6 |
| Rutger Hauer | Joseph Peach | 6 |
| Holland Roden | Zoe Woods | 6 |
| Luisa d'Oliveira | Amy Welch | 6 |
| Steven Weber | Abel Carnacki | 6 |
| John Carroll Lynch | John Sleator | 6 |
| Maria Sten | Jillian Hope Hodgson | 6 |
| Aisha Dee | Jules Koja | 6 |
| Seamus Patterson | J.D. Shields | 6 |
| Jeff Ward | Seth Marlow | 6 |
| Sebastian Pigott | Dylan Evans | 6 |
| Olivia Luccardi | Alice Woods | 6 |
| Steven Robertson | Ian | 6 |
| Barbara Crampton | Vanessa Moss | 6 |
| Brandon Scott | Luke Vanczyk | 6 |
| Brandon Scott | Tom Hodgson | 6 |
| Shaun Benson | Gary Yolen | 6 |
| Paul Schneider | Mike Painter | 6 |
| Marina Stephenson Kerr | Frances Booth | 6 |
| Jess Salgueiro | Lacy Evans | 6 |
| Amy Forsyth | Margot Sleator | 6 |
| Luca Villacis | Eddie Painter / Mike Painter (young) | 6 |
| Krisha Fairchild | Louise Lispector | 6 |
| Melanie Nicholls-King | Brenna Koja | 6 |
| Natalie Brown | Jessica Yolen | 6 |
| Greg Bryk | Det. McPhillips | 4 |
| Quinton Boisclair | The Pestilent God | 4 |
| Connor Peterson | Jacob Booth | 4 |
| Julian Richings | The Gardener | 3 |
| Quinton Boisclair | The Pestilent God / Spindly Father Time | 1 |
| Nazariy Demkowicz | Ben | 1 |