| Laura Diamond, a brilliant NYPD homicide detective balances her “Columbo” day job with a crazy family life that includes two unruly twin boys and a soon-to-be ex-husband — also a cop — who just can't seem to sign the divorce papers. Between cleaning up after her boys and cleaning up the streets, she’d be the first to admit she has her “hot mess” moments in this hilariously authentic look at what it really means to be a “working mom” today. Somehow, she makes it all work with the help of her sexy and understanding partner, and things becomes even more complicated when her husband, ironically, becomes her boss at the precinct. For Laura, every day is a high-wire balancing act. |
| Name | Character | Episodes |
|---|---|---|
| Debra Messing | Detective Laura Diamond | 38 |
| Laz Alonso | Billy Soto | 38 |
| Josh Lucas | Jake Broderick | 38 |
| Janina Gavankar | Meredith Bose | 38 |
| Max Jenkins | Max Carnegie | 38 |
| Callie Thorne | Captain Nancy Santiani | 16 |
| Neal Bledsoe | Tony Abbott | 11 |
| Meg Chambers Steedle | Francesca 'Frankie' Pulaski | 8 |
| Robert Klein | Leo Diamond | 5 |
| Enrico Colantoni | Dan Hauser | 3 |
| Jenna Fischer | Jennifer Lambert | 3 |
| Lynn Marocola | Police Officer (uncredited) | 3 |
| Debby Ryan | Lucy Diamond | 2 |
| Jerry O'Connell | Jon Dunham | 2 |
| Stockard Channing | Brenda Phillips | 2 |
| Kahyun Kim | Sammi | 2 |
| Clara Wong | Ayla | 2 |
| Remy Auberjonois | Dr. Evanston | 2 |
| Richard Hughes | Michael Dunham | 2 |
| Betty Gilpin | Isabel Van Doren | 1 |
| Harold Perrineau | Charles Baptiste | 1 |
| Wallace Shawn | Kenneth Walters | 1 |
| Cara Buono | Julia Davis | 1 |
| Courtney Henggeler | Nora | 1 |
| Steve Guttenberg | Steve Guttenberg | 1 |
| Peter Jacobson | Russell | 1 |
| Dan Butler | Calvin Gold | 1 |
| Ashlei Sharpe Chestnut | Receptionist / Becky | 1 |
| Sarah Utterback | Angela Sarkissian | 1 |
| Hayley Griffith | Sara Shaw | 1 |
| Malachy Cleary | Chief D'Angelo | 1 |
| Juan Carlos Hernández | Victor Santos | 1 |
| Brian McCarthy | Clerk | 1 |
| Juliana Aidén Martinez | Faith McGowan | 1 |
| Vanessa Kai | Marcia Collinsworth | 1 |
| Louis Vanaria | Lawyer | 1 |
| Yasha Jackson | Lisa | 1 |
| Willie Garson | Georges Tilleu aka The Nose | 1 |
| Mercedes Ruehl | Val Santiani | 1 |
| Scott Cohen | Vince Deluca | 1 |
| Alysia Reiner | Liz Walters | 1 |
| Miriam Shor | Eleanor Caldecott | 1 |
| Brenda Strong | Margot Preston | 1 |
| Melissa Joan Hart | KC Moss | 1 |
| Michelle Hurd | Donna McKinney | 1 |
| Pej Vahdat | Kasib Al Wazir | 1 |
| Eric McCormack | Dr. Andrew Devlin | 1 |
| Gilles Marini | Tom Burke | 1 |
| Kelly Rutherford | Lisa Hanlon | 1 |
| Bronson Pinchot | Head Chef J.T. Thompson | 1 |
| Gabriel Mann | Shane Allen | 1 |
| Polly Draper | Ruby | 1 |
| James Martinez | Carlos Hernandez | 1 |
| Janel Parrish | Jillian Havemeyer | 1 |
| Meta Golding | Special Agent Barrington | 1 |
| Tate Donovan | Detective Malcolm Harris | 1 |
| John Rothman | Pastor Bob | 1 |
| Henrique Zaga | Theo Barnett | 1 |
| Adriane Lenox | Ms. Parker | 1 |
| Johnny Hopkins | Spike | 1 |
| Joy Osmanski | Linda Singer | 1 |
| Sean Cullen | Lieutenant Monahan | 1 |
| Hari Dhillon | Swami Sanjay | 1 |
| Christopher Neiman | Elliot | 1 |
| Andrew Rothenberg | Dr. Nick | 1 |
| Jake Choi | Calvin Wu | 1 |
| Jay Hieron | Biker Dude | 1 |
| Dan Grimaldi | Bosco | 1 |
| Kathie Lee Gifford | Dr. Carlin | 1 |
| Lou Martini Jr. | Ferry Captain | 1 |
| Josh Banks | Hotel Manager | 1 |
| Taryn Reif | Brianna | 1 |
| Briana Marin | Heather | 1 |
| Greg Grunberg | Kurt Baronson | 1 |
| Kenny Smith | Kenny Smith | 1 |
| Paulina Porizkova | Charlotte Bernice | 1 |
| Karina Arroyave | Housekeeper | 1 |
| Aaron Moten | Ben Lee | 1 |
| Brian Donahue | City Driver | 1 |
| Anastasia Griffith | Angela Ryan | 1 |
| Ned Eisenberg | Julius Sarkissian | 1 |
| Erin Anderson | Maureen Ross | 1 |
| James Ciccone | Line Guy | 1 |
| Rony Clanton | Officer Hampton | 1 |
| Leslie Hendrix | Trish | 1 |
| Geneva Carr | Danielle Bailey | 1 |
| Regina Taylor | Mrs. Campbell | 1 |
| Patrick Breen | Erik Walden | 1 |
| Kaili Vernoff | Jenny | 1 |
| Aaron Yoo | Chris Lee | 1 |
| Frankie Muniz | Frankie Muniz | 1 |
| Peter Francis James | Titus Bosch | 1 |
| Marisa Ryan | Susan | 1 |
| Madison Arnold | Seymour | 1 |
| John Palladino | Brian Hill | 1 |
| Ari Fliakos | Donovan Breva | 1 |
| Orlagh Cassidy | Pamela Baker | 1 |
| Amy Hargreaves | Nancy Santamaria | 1 |
| Andrew Pang | Lalo Pescar | 1 |
| David Starzyk | Jason Harvell | 1 |
| Parisa Fitz-Henley | Bridget Flowers | 1 |
| Anna Baryshnikov | Tracy Dunn | 1 |
| Marylouise Burke | Mrs. Delvecchio | 1 |
| Lolita Foster | Court Officer | 1 |
| Linda Powell | Rosalie Romero | 1 |
| Danny Johnson | Michael Forster | 1 |
| Sherri Saum | Cecilia Burke | 1 |
| Bill Hoag | Police Chief | 1 |
| Adam Shapiro | Cody Roberts | 1 |
| Alexandra Turshen | Nurse | 1 |
| Michael Sirow | Wall Street | 1 |
| Matt Walton | Reporter Store | 1 |
| Jason Alan Carvell | Mike Jameson | 1 |
| Jamar Greene | Tow Truck Driver | 1 |
| Jimmy Palumbo | Sam Marks | 1 |
| Alfred Sauchelli, Jr. | Worker | 1 |
| Ruffin Prentiss | Shifty / Carlos | 1 |
| Anthony Mangano | Bob | 1 |
| Erika Rolfsrud | Trashy Woman | 1 |
| Kira Sternbach | Heidi Feld | 1 |
| Elliot Villar | Yasiel Leon | 1 |
| Michael Masini | Wes Davis | 1 |
| Julian Cihi | Aaron James | 1 |
| Ricky Paull Goldin | Charlie Carazzo | 1 |
| Aimee Mullins | Connie Baker | 1 |
| Christian Campbell | Councilman Danvers | 1 |
| Alex Esola | Frat Boy | 1 |
| Lynn Marocola | Crime Scene Unit (uncredited) | 1 |
| Lynn Marocola | TSA Agent (uncredited) | 1 |
| Kerry Butler | Zoey's Mom | 1 |
| Eva Kaminsky | Vicky Lynn | 1 |
| Azhy Robertson | Eli | 1 |
| Chazz Menendez | Pitbull | 1 |
| Anton Narinskiy | Slava Krupski | 1 |
| Alex Huynh | Tai Chi Instructor | 1 |
| Michael Rivera | Shuttle Driver | 1 |
| Nicole Ansari-Cox | Gabriella Luca | 1 |
| Jojo Gonzalez | Mr. Randazi | 1 |
| Marta Milans | Valeria Hernandez | 1 |
| John Harrington Bland | Doorman | 1 |
| Michael Genet | Captain Meeks | 1 |
| Erik Heger | Roan Wilbur | 1 |
| Keenan Shimizu | Sammi's Dad | 1 |
| Larry Mitchell | Major Sherman | 1 |
| Chloë Levine | Ally Davis | 1 |
| Celestine Rae | Rosaline | 1 |
| Samuel Stricklen | Desk Clerk | 1 |
| Steve Routman | Cyrus Speeler | 1 |
| Jeffrey Pierce | Terrence Van Doren | 1 |
| Raj Kala | Sales Clerk | 1 |
| Kathleen Garrett | Helen | 1 |
| Erin Dilly | Sara Wexler | 1 |
| Krysta Rodriguez | April Watkins | 1 |
| Florencia Lozano | Dr. Lens | 1 |
| Matthew Sean Blumm | MC Firm | 1 |
| Alexandra Silber | Agitated Mom | 1 |
| Quincy Chad | TJ Cantrell | 1 |
| David Anthony Buglione | Bearded Biker / Kyle Dunley | 1 |
| David Anthony Buglione | Gunman | 1 |
| David Valcin | Richard LeDeux | 1 |
| Nick Mathews | Boyfriend | 1 |
| Burke Moses | Peter Chase | 1 |
| Brennan Taylor | Bartender | 1 |
| Dawn-Lyen Gardner | Samantha Williams | 1 |
| J.W. Cortes | FBI Special Agent Lewis | 1 |
| Sheila Tapia | Carmen | 1 |
| Morgan McGarry | April | 1 |
| P.J. Marshall | Wayne Lewis | 1 |
| Nicholas Wyman | Principal | 1 |
| Victor of Aquitaine | Beno | 1 |
| Sam Haft | Harry Rice | 1 |
| Justin Lord | Judge | 1 |
| Blaire Brooks | Patty | 1 |
| Will Blagrove | Norris | 1 |
| Robert Turano | Father Tom | 1 |
| Peter Rini | Carl Davis | 1 |
| Jordan Dean | Ethan Skinner | 1 |
| Matthew James Ballinger | Barista | 1 |
| Kati Rediger | Shop Girl | 1 |
| Matthew F. O'Connor | Dumpy Guy | 1 |
| Ty Jones | Phil Hooks | 1 |
| Meredith Handerhan | Tense Driver | 1 |
| Dave Shalansky | William Davis | 1 |
| Gregory Bastien | Devin | 1 |
| Peter Falls | Valet Parker | 1 |
| Samia Akudo | Hostess | 1 |
| Gameela Wright | Public Defender | 1 |
| Bryan Terrell Clark | Trent Hawthorne | 1 |
| Alesandra Assante | Salina | 1 |
| Philip Hernandez | Karl Moseman | 1 |
| Mauricio Ovalle | Matthew Sanchez | 1 |
| Wakeema Hollis | Natalie Marquez | 1 |
| Toni D'Antonio | Nurse Elena | 1 |
| Mark Vincent | Bodyguard | 1 |
| Joe Hansard | Homeless Guy | 1 |
| Stevie Steel | Maya | 1 |
| Kevin Collins | David Ackerman | 1 |
| Andrew Hovelson | Vladi | 1 |
| Nadine Malouf | Andrea | 1 |
| Dana Eskelson | Gloria Leighton | 1 |
| Christopher Innvar | Costas Andropos | 1 |
| Jeb Kreager | Roger Wexler | 1 |
| Taylor Rose | Candace Davis | 1 |
| Mike Massimino | Hot Dog Vendor | 1 |
| Oleg Ossayenko | Coach | 1 |
| Carmen Cabrera | valentina | 1 |
| Daniel Farcher | Bartender | 1 |
| Emily Rutherfurd | Dawn Grant | 1 |
| Anthony DeVito | Janitor | 1 |
| Meredith Travers | Sloane | 1 |
| Brandon Espinoza | Ian Gendry | 1 |
| Joseph Mesiano | Jean-Luc | 1 |
| Jim Ford | Ronald | 1 |
| Frank Harts | Derry Donnigan | 1 |
| Tina Benko | Judith Hansen | 1 |
| Franky G | Lyle Truco | 1 |
| William Lex Ham | Criminal | 1 |
| Rona Figueroa | Alison Torres | 1 |
| Samantha Ivers | Drea Moretti | 1 |
| Los Jones | Red Jersey | 1 |
| Joseph Tudisco | Cleaner | 1 |