Popularity: 3
| Creator: | Amy Holden Jones | 
|---|
| Catherine Black is a world-famous neurologist at the state-of-the-art medical institution known as "The Cube". Catherine is brilliant, beautiful, and at the top of her game, though she's hiding a secret of her own: she's bipolar. Each week, the doctors on staff attempt to unravel the mysteries of the brain and are constantly challenged by cases never-before-seen on television. The medical stories are moving, bizarre and a visual feast. The personal stories are riveting. The patients have rare, highly visual, often hallucinogenic and startling conditions, which we’ll see through their eyes as Catherine diagnoses and treats them. | 
| Name | Character | Episodes | 
|---|---|---|
| Kelly Reilly | Dr. Catherine Black | 13 | 
| Laura Fraser | Regan Black | 13 | 
| Terry Kinney | Dr. Owen Morely | 13 | 
| Vanessa Redgrave | Dr. Hartramph | 13 | 
| David Chisum | Joshua Black | 13 | 
| Ali Wong | Dr. Lina Lark | 13 | 
| David Ajala | Will Van Renseller | 13 | 
| Siobhan Williams | Esme Black | 13 | 
| Ditch Davey | Dr. Ian Bickman | 13 | 
| Aja Naomi King | Ali Henslee | 8 | 
| Sawyer Barth | Young Joshua Black | 3 | 
| David Rasche | Hunter Black | 1 | 
| Tom Pelphrey | Joseph Moran | 1 | 
| Trini Alvarado | Beatrice King | 1 | 
| Tasso Feldman | Leo Robinson | 1 | 
| Arian Moayed | Cyrus | 1 | 
| Peter Maloney | Harry | 1 | 
| Audrey Esparza | Carlotta | 1 | 
| Brendan Griffin | Young Hunter | 1 | 
| Michael Pemberton | Lionel Stark | 1 | 
| Joel Perez | Mexican Carson | 1 |