| Name | Character | Episodes |
|---|---|---|
| Frank Welker | Bo / Booker / Sheldon (voice) | 363 |
| Howard Morris | Wade (voice) | 363 |
| Gregg Berger | Odie / Orson (voice) | 363 |
| Julie Payne | Dr. Liz / Lanolin (voice) | 363 |
| Desiree Goyette | Nermal (voice) | 363 |
| Thom Huge | Jon Arbuckle / Roy / Binky the Clown (voice) | 363 |
| Lorenzo Music | Garfield (voice) | 363 |
| Pat Buttram | Cactus Jake (voice) | 3 |
| Lennie Weinrib | 2 | |
| Larry Storch | 2 | |
| Stan Freberg | 2 | |
| June Foray | 1 | |
| Carl Ballantine | 1 | |
| Paul Winchell | 1 | |
| Neil Ross | 1 | |
| Pat Buttram | Voice | 1 |
| John Stocker | 1 | |
| Ami Foster | 1 | |
| Chick Hearn | 1 | |
| Chuck McCann | 1 | |
| Jim Davis | 1 | |
| Victoria Jackson | Penelope | 0 |