| Name | Character | Episodes |
|---|---|---|
| Sally Martin | Nicole Miller | 7854 |
| Ben Mitchell | Te Koha "TK" Samuels | 7854 |
| Liddy Holloway | Alex McKenna | 2258 |
| Paolo Rotondo | Andrew Solomon | 2254 |
| Amanda Billing | Sarah Potts | 2017 |
| Anna Jullienne | Maia Jeffries | 2017 |
| Claire Chitham | Waverley Wilson/Harrison | 1992 |
| Ben Mitchell | TK Samuels | 1510 |
| Angela Marie Dotchin | Kirsty Knight | 1400 |
| Beth Allen | Brooke Freeman | 1005 |
| Martin Henderson | Stuart Neilson | 920 |
| Temuera Morrison | Hone Ropata | 920 |
| Craig Parker | Guy Warner | 920 |
| Rene Naufahu | Sam Aleni | 920 |
| Elizabeth McRae | Marj Neilson | 920 |
| Mark Ferguson | Darryl Neilson | 920 |
| Paul Gittins | Michael McKenna | 920 |
| John Leigh | Lionel Skeggins | 766 |
| Simon Prast | Paul Churchill | 766 |
| Chic Littlewood | Laurie Brasch | 766 |
| Tom Hern | Baxter Cormack | 755 |
| Martyn Sanderson | Noel Sturgess | 675 |
| Karl Urban | Jamie Forrest | 521 |
| Marton Csokas | Leonard Dodds | 521 |
| Margaret Umbers | Katherine Blake | 521 |
| Olivia Tennet | Tuesday Warner | 505 |
| Timothy Balme | Greg Feeney | 501 |
| Robyn Malcolm | Ellen Crozier | 501 |
| Claire Chitham | Waverley Wilson | 501 |
| Lynette Forday | Grace Kwan | 501 |
| Jo Briant | Ruth Brasch | 501 |
| Donna Akersten | Marilyn Bluck | 501 |
| Robbie Magasiva | Maxwell Avia | 500 |
| Manu Bennett | Jack Hewitt | 485 |
| Carrie McLaughlin | Nurse Mere Johnson | 485 |
| Danielle Cormack | Alison Raynor | 419 |
| Willa O'Neill | Serena Hughes | 419 |
| Kevin J. Wilson | Declan Kennedy | 265 |
| Rod Mullinar | Max Dubrovsky | 260 |
| Todd Emerson | Cody Bell | 260 |
| Joseph Naufahu | Nat Aleni | 256 |
| Richard Vette | Tim Cunningham | 256 |
| Roimata Fox | Tariana Harris | 250 |
| Min Kim | Winston Youn | 250 |
| Sally Martin | Nicole Martin | 250 |
| Marton Csokas | Leonard Rossi-Dodds | 245 |
| Peter McCauley | Finlay Keats | 245 |
| Joel Tobeck | Craig Develter | 245 |
| Mike Edward | Zac Smith | 245 |
| Dean O'Gorman | Harry Martin | 245 |
| James Napier Robertson | Glen McNulty | 245 |
| Blair Strang | Rangi Heremaia | 245 |
| Timothy Bartlett | Bernie Leach | 245 |
| Meighan Desmond | Lulu Chatfield | 245 |
| Elizabeth Hawthorne | Julia Thornton | 245 |
| Caleb Ross | Logan Patterson | 243 |
| Mark Ferguson | Damien Neilson | 243 |
| Jennifer Ludlam | Leanne Black | 240 |
| Alistair Browning | Barry Harrison | 154 |
| Shimpal Lelisi | Nurse Louie Iosefa | 9 |
| Amber-Rose Henshall | Lizzie Elliot | 6 |
| Jonathan James | Connor Stuart | 2 |
| K.J. Apa | Kane Jenkins | 1 |
| Sarah McLeod | Cindy Watson | 1 |
| Jordi Webber | Jake Morris | 1 |
| Bonnie Soper | Morgan Braithwaite | 1 |