| Name | Character | Episodes |
|---|---|---|
| Jack Warner | PC George Dixon | 433 |
| Peter Byrne | Andy Crawford | 433 |
| Nicholas Donnelly | Johnny Wills | 288 |
| Graham Ashley | PC Tommy Hughes | 40 |
| Graham Ashley | Det. Con. Tommy Hughes | 39 |
| Robert Cawdron | Det. Insp. Cherry | 28 |
| Robert Raglan | Superintendent | 13 |
| Ben Howard | DC Len Clayton | 8 |
| Richard Heffer | DS Alan Bruton | 8 |
| Geoffrey Keen | Det. Supt. Harvey | 4 |
| Roy Holder | Gordon Brown | 2 |
| Patrick Godfrey | Dr. Hobbs | 2 |
| Godfrey James | Foreman | 2 |
| Michael Brennan | Jack Kelly | 2 |
| Tom Adams | Jack Montelbetti | 2 |
| George A. Cooper | Topper Brown | 2 |
| Sean Connery | Joe Brasted | 1 |
| John Rhys-Davies | Dunlop | 1 |
| Steven Berkoff | Dave Banks | 1 |
| Muriel Pavlow | Anne Fulton | 1 |
| Ray Barrett | Phil Burgh | 1 |
| Wendy Richard | Jean Davis | 1 |
| Wendy Richard | Barbara Walker | 1 |
| Brian Murphy | Percy Sinclair | 1 |
| Floella Benjamin | Mrs. Dallas | 1 |
| John Carson | Joe Conway / Francis Spurling | 1 |
| Michael Golden | Sammy MacBride | 1 |
| Julian Glover | Lewis Naylor | 1 |
| Martin Jarvis | Vic Hallan | 1 |
| Joan Hickson | Elsie Francis | 1 |
| Barbara Shelley | Edwina | 1 |
| Richard O'Sullivan | Cris Patros | 1 |
| Michael Crawford | Howard Garland | 1 |
| Jimmy Gardner | Higgins | 1 |
| Jimmy Gardner | Charlie Wicks | 1 |
| Jimmy Gardner | Sniffy Baker | 1 |
| Tom Baker | The Man | 1 |
| Tom Baker | Foreman | 1 |
| John Bennett | Victor Lane | 1 |
| John Bennett | Malcolm Roberts | 1 |
| Michael Goodliffe | Garfield Fenton | 1 |
| Patrick O'Connell | Nobby Clark | 1 |
| Patrick O'Connell | Willy | 1 |
| Bernard Fox | Smiler Hodges | 1 |
| Phyllida Law | Rosie McCallion | 1 |
| Angela Pleasence | Alice Benfield | 1 |
| John Salthouse | Cliff | 1 |
| Patrick Mower | Clifford Abel | 1 |
| Colin Farrell | John Hayward | 1 |
| Roger Lloyd Pack | Ron Fielding | 1 |
| Cheryl Hall | Rita Batty | 1 |
| Frank Middlemass | Scully | 1 |
| Frank Middlemass | Billy the Tramp | 1 |
| Frank Middlemass | Morrie | 1 |
| Anita Carey | Carol Hayward | 1 |
| Rodney Bewes | PC Screen | 1 |
| Desmond Llewelyn | Det. Insp. Jones | 1 |
| Desmond Llewelyn | Dr. Pearce | 1 |
| Desmond Llewelyn | Bank Manager | 1 |
| Leslie French | Bert Dunnett | 1 |
| Richard Briers | Ken Tracey | 1 |
| John Savident | Van Heerden | 1 |
| Michael Sheard | Reporter | 1 |
| Michael Sheard | 2nd Cabbie | 1 |
| Michael Sheard | 1st Patrol Officer | 1 |
| Michael Sheard | Night Porter | 1 |
| Cyril Shaps | Green | 1 |
| Colin Douglas | Mr. Stevens | 1 |
| Barry Jackson | Roy Sharp | 1 |
| Barry Jackson | Bobby Brown | 1 |
| Barry Jackson | Joe | 1 |
| Geoffrey Keen | John Armitage | 1 |
| Isla Blair | Fleur Harris | 1 |
| Walter Gotell | Gooch | 1 |
| Anton Diffring | Charles Mason | 1 |
| Nick Tate | Don Ross | 1 |
| David Janson | Dave | 1 |
| Charles Lloyd Pack | Ben Waterfield | 1 |
| Michael Graham Cox | Davis | 1 |
| Michael Graham Cox | Brian Kent | 1 |
| Brian Glover | Chuck Windell | 1 |
| Frederick Jaeger | John Charles Walton | 1 |
| Paul Eddington | Mr. Birch | 1 |
| Glyn Houston | Woody | 1 |
| Peter Diamond | Alexander Mackay | 1 |
| Earl Cameron | John Tate | 1 |
| Robert Cawdron | Insp. Gordon | 1 |
| Gerald Sim | Mr. Worth | 1 |
| Gerald Sim | Mr. Golding | 1 |
| Gerald Sim | Police Surgeon | 1 |
| Ballard Berkeley | Mr. Noakes | 1 |
| Ballard Berkeley | Mr. Briggs | 1 |
| Ballard Berkeley | Mac | 1 |
| Ballard Berkeley | Charles Devenish | 1 |
| Ballard Berkeley | Victor Dowson | 1 |
| Ballard Berkeley | Joe Magnus | 1 |
| Ballard Berkeley | Harry Bates | 1 |
| Ballard Berkeley | Colonel | 1 |
| Maurice O'Connell | Frank Page | 1 |
| Brian Wilde | Clayton | 1 |
| Brian Wilde | Henry Brandon | 1 |
| Peter Bull | Arthur Coburn | 1 |
| Frank Thornton | PC Cox | 1 |
| Glynn Edwards | David Caley | 1 |
| Glynn Edwards | Det. Sgt. Frank Harvey | 1 |
| Andrew Faulds | Jock MacPherson | 1 |
| Thora Hird | Alice Leggett | 1 |
| Vernon Dobtcheff | Counsel for Defence | 1 |
| Patrick Godfrey | Dr. Walsh | 1 |
| Jerold Wells | Sgt. Muir | 1 |
| Jerold Wells | Trotter Kelly | 1 |
| Jerold Wells | Henry Galloway | 1 |
| William Lucas | Philip Chapman | 1 |
| Godfrey James | Sgt. Dodds | 1 |
| Godfrey James | Mellish | 1 |
| John Junkin | Dan Stuart | 1 |
| Neil McCarthy | Frankie Clark | 1 |
| Ronald Leigh-Hunt | Brown | 1 |
| Stephen Greif | Tony | 1 |
| Stephen Greif | Det. Chief Insp. Basset | 1 |
| Stephen Greif | Charles Negri | 1 |
| Robert Brown | Dick Hastings | 1 |
| Helen Fraser | Gwen | 1 |
| Kenneth Cope | Harold Tovey | 1 |
| Anna Wing | Mrs. Porter | 1 |
| David Spenser | Chatterjee | 1 |
| Derek Martin | Len Drake | 1 |
| Arnold Diamond | Assistant Hotel Manager | 1 |
| Robert Raglan | Superintendent (uncredited) | 1 |
| Robert Raglan | Herbert Franklin | 1 |
| Robert Raglan | Judge | 1 |
| Richard Vernon | Mr. Pascoe | 1 |
| Richard Vernon | Mr. Fellowes | 1 |
| John Phillips | Magistrate | 1 |
| Sue Nicholls | Renee | 1 |
| Sue Nicholls | Myra Close | 1 |
| Clifford Rose | Bernie Katz | 1 |
| Harry Towb | Reg Bishop | 1 |
| Harry Towb | Fred | 1 |
| Tommy Duggan | Billo Burke | 1 |
| Terence Rigby | PC Smith | 1 |
| Terence Rigby | PC Jacks | 1 |
| Aimée Delamain | Mrs. Lane | 1 |
| Aimée Delamain | Miss Matty | 1 |
| Michael Brennan | Tiny Allbright | 1 |
| Michael Brennan | Jack Kelly (uncredited) | 1 |
| Michael Brennan | Mr. Warren | 1 |
| Michael Brennan | Joe Duckett | 1 |
| Michael Brennan | Mr. Smethers | 1 |
| Michael Brennan | Danny McCallion | 1 |
| Michael Brennan | Fenton | 1 |
| Hamilton Dyce | Mr. Styler | 1 |
| Guy Middleton | Fred Harper | 1 |
| Mervyn Johns | Mr. Farmer | 1 |
| Sally Faulkner | Annabelle Sturmer | 1 |
| Geoffrey Hinsliff | Doctor | 1 |
| Richard Davies | Haines | 1 |
| Richard Davies | Milkman | 1 |
| Richard Davies | Det. Chief Insp. Pearce | 1 |
| Frank Mills | Milkman | 1 |
| Erik Chitty | Bert | 1 |
| Erik Chitty | Nightwatchman | 1 |
| Erik Chitty | Tosh | 1 |
| Martin Boddey | Mark Taylor | 1 |
| Derek Newark | Eddie Brown | 1 |
| Margaret John | Jenny | 1 |
| Michael Balfour | Joe Ward | 1 |
| Michael Balfour | Pip Rutley | 1 |
| Michael Balfour | Bill Nelson | 1 |
| Michael Balfour | Nicky Medwin | 1 |
| Michael Balfour | Hobbs | 1 |
| Tim Barlow | Boscombe | 1 |
| Alan Tilvern | Morrie Finn | 1 |
| Michael Lees | Mr. Hayes | 1 |
| Glyn Owen | Victor Davis | 1 |
| Jeremy Young | McCleod | 1 |
| Gwyneth Powell | Mrs. Regan | 1 |
| Anthony Bate | PC Bert Scott | 1 |
| Anthony Bate | PC Downing | 1 |
| Larry Martyn | Coffee Bar Attendant | 1 |
| David Daker | Headmaster | 1 |
| Anne Stallybrass | Mary Brown | 1 |
| Jim McManus | Vic | 1 |
| John Comer | Greengrocer | 1 |
| Ewen Solon | Captain Lewis | 1 |
| Gretchen Franklin | Mrs. Walcott | 1 |
| Royston Tickner | Bruce | 1 |
| Noel Howlett | Mr. Bodley | 1 |
| George Layton | Billy Tate | 1 |
| Graham Ashley | Det. Sgt. Tommy Hughes | 1 |
| Graham Ashley | TV Enquiry Officer | 1 |
| Bernard Horsfall | John Harris | 1 |
| Trevor Bannister | Eddie Farrell | 1 |
| Jo Rowbottom | Julie Taylor | 1 |
| Jo Rowbottom | Rosie Everett | 1 |
| Jo Rowbottom | Joyce | 1 |
| Jill Gascoine | Lorna McDermot | 1 |
| Michael Craze | Hyett | 1 |
| Olaf Pooley | Mark Fuller | 1 |
| Olaf Pooley | Captain Bailey | 1 |
| Paul Darrow | Pearce | 1 |
| Paul Darrow | Tony Kinsley | 1 |
| Peter Denyer | Phil Bremmer | 1 |
| Ellis Dale | Mr. Carpenter | 1 |
| Mary Hignett | Mrs. Venables | 1 |
| Ann Morrish | Lorna Harris | 1 |
| Bert Palmer | Mr. Cox | 1 |
| Richard Shaw | Peter Morell | 1 |
| Patrick McAlinney | Happy Day | 1 |
| Christine Finn | Sheila Lane | 1 |
| Peter Purves | Brian | 1 |
| Lennard Pearce | Mr. Kemp | 1 |
| Sylvia Coleridge | Mrs. Collins | 1 |
| John Harvey | Dr. Ingrams | 1 |
| John Harvey | Col Ryman | 1 |
| John Harvey | Mr. Harper | 1 |
| Donald Gray | Paul Merton | 1 |
| Jonathan Adams | 1 | |
| Peter Birrel | Mick Bowyer | 1 |
| Peter Craze | Bob Reynolds | 1 |
| Prentis Hancock | Det. Sgt. Stainer | 1 |
| Tom Adams | Charlie Mann | 1 |
| Tom Adams | Johnny Orwell | 1 |
| Kevin Stoney | Bert Rogers | 1 |
| Luan Peters | Marie | 1 |
| June Whitfield | Marie | 1 |
| June Brown | Brenda Walker | 1 |
| Windsor Davies | Vic Sharland | 1 |
| Windsor Davies | Jack Winstone | 1 |
| George A. Cooper | Jackson | 1 |
| George A. Cooper | Monty Pitman | 1 |