| Name | Character | Episodes |
|---|---|---|
| Will Lyman | Self - Narrator (voice) | 824 |
| Judy Woodruff | Self - Host | 91 |
| Jessica Savitch | Self - Host | 25 |
| Donald Trump | Self (archive footage) | 5 |
| Barack Obama | Self (archive footage) | 3 |
| Louie Gohmert | Self (archive footage) | 3 |
| Hillary Clinton | Self (archive footage) | 2 |
| Vladimir Putin | Self | 2 |
| Kamala Harris | Self (archive footage) | 2 |
| George W. Bush | Self (archive footage) | 2 |
| Laura Bush | Self (archive footage) | 2 |
| Nancy Pelosi | Self (archive footage) | 2 |
| Jared Kushner | Self (archive footage) | 2 |
| Jill Biden | Self (archive footage) | 2 |
| Barbara Bush | Self (archive footage) | 2 |
| Malia Ann | Self (archive footage) | 2 |
| Sophie Okonedo | Narrator | 1 |
| Melania Trump | Self (archive footage) | 1 |
| Malcolm X | Self (archive footage) | 1 |
| Michelle Obama | Self (archive footage) | 1 |
| Al Gore | 1 | |
| Ronald Reagan | Self (archive footage) | 1 |
| Mark Zuckerberg | Self (archive footage) | 1 |
| Joe Biden | Self (archive footage) | 1 |
| Joe Biden | Self | 1 |
| Donald Trump Jr. | Self (archive footage) | 1 |
| Trevor Howard | Narrator (voice) | 1 |
| Bill Clinton | Self (archive footage) | 1 |
| Tucker Carlson | Self (archive footage) | 1 |
| Larry Storch | 1 | |
| Rudolph Giuliani | Self (archive footage) | 1 |
| Will Lyman | Self, Narrator | 1 |
| Will Lyman | Narrator (voice) | 1 |
| Seth Meyers | Self (archive footage) | 1 |
| George H. W. Bush | Self (archive footage) | 1 |
| Chuck Schumer | Self (archive footage) | 1 |
| Roger Stone | Self (archive footage) | 1 |
| Roger Stone | Self | 1 |
| Mike Pence | Self (archive footage) | 1 |
| Eric Trump | Self (archive footage) | 1 |
| Bernie Sanders | Self (archive footage) | 1 |
| Megyn Kelly | Self | 1 |
| Xi Jinping | Self (archive footage) | 1 |
| Marjorie Taylor Greene | Self (archive footage) | 1 |
| Dmitry Medvedev | Self | 1 |
| John McCain | Self (archive footage) | 1 |
| Joy Reid | Self (archive footage) | 1 |
| Prince Mohammed bin Salman al Saud | Himself | 1 |
| Colin Powell | Self | 1 |
| JD Vance | Self (archive footage) | 1 |
| Tiffany Trump | Self (archive footage) | 1 |
| Rajiv Chandrasekaran | Self | 1 |
| Anita Hill | Self (archive footage) | 1 |
| Amal Clooney | Self | 1 |
| Vivek Ramaswamy | Self | 1 |
| Chelsea Clinton | Self (archive footage) | 1 |
| Tim Walz | Self (archive footage) | 1 |
| Ivana Trump | Self (archive footage) | 1 |
| Rodrigo Duterte | Self | 1 |