| Name | Character | Episodes |
|---|---|---|
| Kyle MacLachlan | Donovan Stark | 8 |
| Kristoffer Polaha | Nolan Adams | 8 |
| Janet Montgomery | Martina Garretti | 8 |
| Megalyn Echikunwoke | Riley Prescott | 8 |
| Felix Solis | River "Riv" Brody | 8 |
| Erin Cummings | Bonnie Garretti | 8 |
| Toni Trucks | Cyndi Vega | 8 |
| Donna Murphy | Darlene Garretti | 2 |
| Ned Eisenberg | Diego Haas | 2 |
| Pablo Schreiber | Luke Aaronson | 1 |
| Cindy Cheung | Nurse | 1 |
| Joseph Siravo | Gavin Garretti | 1 |
| Antonio Ortiz | Boy | 1 |
| Kevin Corrigan | Curran Papke | 1 |
| Stephanie March | Natalie Minka | 1 |
| Peter Friedman | Henry Sohn | 1 |
| Albert Jones | Creston Samms | 1 |
| Ben Shenkman | Andrew Treaster | 1 |
| Annaleigh Ashford | Jackie | 1 |
| Santino Fontana | ADA Van Pelt | 1 |
| Alexandra Socha | Ellie Fordham | 1 |
| David Pittu | Vogel (uncredited) | 1 |
| Teddy Coluca | Janitor | 1 |
| Gretchen Egolf | Karenna Druss | 1 |
| Helen Coxe | Ellie's Mother | 1 |
| Christopher Mann | Harrison Watkins | 1 |
| Remy Auberjonois | Ron Denault | 1 |
| D.K. Bowser | Superintendent | 1 |
| Elaine Bromka | Lois | 1 |
| Julian Gamble | Martin Ross | 1 |
| Mark Gessner | Bridge Officer | 1 |
| Gabriel Ebert | Carter Gershan | 1 |
| Montego Glover | Raquel (uncredited) | 1 |
| Meredith Patterson | Sarah Jenkins | 1 |
| Bridget Megan Clark | Jessie | 1 |
| Elizabeth Stanley | Phebe Larkin | 1 |
| Jessica Blank | Deb Keenan | 1 |
| Sam Rosen | Eric Jenkins | 1 |
| Drew Beasley | Charlie Garretti (uncredited) | 1 |
| Danielle Kotch | Clara | 1 |