| Name | Character | Episodes |
|---|---|---|
| Ashley Johnson | Mary Margaret Doolan | 22 |
| William Devane | Lou Della Rosa | 22 |
| Sara Rue | Monica | 22 |
| Judith Light | Dianne Doolan | 22 |
| Todd Louiso | Brian Doolan | 22 |
| Angela Goethals | Angela Doolan | 22 |
| Jennifer Lien | Roanne | 22 |
| Beverley Mitchell | Clare | 2 |
| Shanelle Gray | 2 | |
| Kathleen Freeman | 1 | |
| Heather Elizabeth Parkhurst | 1 | |
| Jerry Mathers | Himself | 1 |