| Kuroo Hazama, also known as "Black Jack," is a legend in the medical world. Famous for being one of the best, as well as not having a license, Hazama and his assistant Pinoko save countless lives that other doctors cannot... for a price; an exorbitant price, in fact, which causes many to view the genius as greedy and heartless. Despite these claims, however, none can deny his skill and the lengths that he will go to treat his patients. This dark medical drama tells the story of the ominous and mysterious world of underground medicine as Black Jack risks his life to cure some of the most bizarre diseases imaginable, even if it means breaking every law in the process. |
| Name | Character | Episodes |
|---|---|---|
| Akio Otsuka | Black Jack (voice) | 12 |
| Yuko Mizutani | Pinoko (voice) | 12 |
| Megumi Hayashibara | Rie (voice) | 1 |
| Megumi Hayashibara | Andrew (voice) | 1 |
| Hideyuki Hori | Koichirou (voice) | 1 |
| Atsuko Tanaka | Abumaru (voice) | 1 |
| Rica Matsumoto | Yuki Nakajima (voice) | 1 |
| Tomomichi Nishimura | Blue Jacket Commander (voice) | 1 |
| Kazuki Yao | Mamoru Sugita (voice) | 1 |
| Akemi Okamura | Kaori Gotou (voice) | 1 |
| Kikuko Inoue | Sayuri (voice) | 1 |
| Fumiko Orikasa | Tsukiko (voice) | 1 |
| Yumi Touma | Minea F. Ross (voice) | 1 |
| Tessyo Genda | General Cruz (voice) | 1 |
| Hochu Otsuka | President Kelly (voice) | 1 |
| Sakiko Tamagawa | Ikehata Himegimi (voice) | 1 |
| Hiromi Tsuru | Sandra (voice) | 1 |
| Masako Katsuki | Capitán Maria Carnera (voice) | 1 |
| Chafurin | Apostle (voice) | 1 |
| Takeshi Aono | Andre (voice) | 1 |
| Katsuhisa Houki | Commander (voice) | 1 |
| Katsuhisa Houki | Bronson (voice) | 1 |
| Toru Furuya | Leslie Harris (voice) | 1 |
| Nozomu Sasaki | Jun (voice) | 1 |
| Yosuke Akimoto | Patric (voice) | 1 |
| Katsunosuke Hori | Voice of Tree (voice) | 1 |
| Yuri Shiratori | Young Koichirou (voice) | 1 |
| Miki Nagasawa | Lawrence (voice) | 1 |
| Toshihiko Seki | Tokio Umetani (voice) | 1 |
| Toshiko Fujita | Kaoru Koni (voice) | 1 |
| Takeshi Watabe | Coronel Estefan (voice) | 1 |
| Aiko Aihashi | Nurse (voice) | 1 |