| Trigun takes place in the distant future on a desert planet. Vash the Stampede is a gunfighter with a legend so ruthless he has a $$60,000,000,000 bounty on his head. Entire towns evacuate at the rumor of his arrival. But the real Vash the Stampede, the enigmatic and conflicted lead character, is more heroic, even though he usually acts like a complete idiot. |
| Name | Character | Episodes |
|---|---|---|
| Satsuki Yukino | Milly Thompson (voice) | 26 |
| Hiromi Tsuru | Meryl Stryfe (voice) | 26 |
| Show Hayami | Nicholas D. Wolfwood (voice) | 26 |
| Masaya Onosaka | Vash the Stampede (voice) | 26 |
| Aya Hisakawa | Rem Saverem (voice) | 8 |
| Toshihiko Seki | Legato Bluesummers (voice) | 7 |
| Rica Matsumoto | Kaito (voice) | 3 |
| Unsho Ishizuka | B.D. Neon (voice) | 2 |
| Koji Ishii | Brad (voice) | 2 |
| Hirotaka Suzuoki | Chapel the Evergreen (voice) | 2 |
| Rei Sakuma | Marianne (voice) | 1 |
| Akio Otsuka | Rai-Dei the Blade (voice) | 1 |
| Hiroshi Kamiya | Zazie the Beast (voice) | 1 |
| Kenichi Ogata | Nebraska (voice) | 1 |
| Miki Ito | Marilyn (voice) | 1 |
| Ryo Horikawa | E.G. Mine (voice) | 1 |
| Yuri Amano | Elizabeth (voice) | 1 |
| Toshiyuki Morikawa | Kesskass (voice) | 1 |
| Nobuo Tobita | Patricia (voice) | 1 |
| Takeshi Aono | Stan (voice) | 1 |
| Hidenari Ugaki | Mohican (voice) | 1 |
| Tetsuya Iwanaga | Julius (voice) | 1 |
| Tomoko Ishimura | Lina (voice) | 1 |