| Name | Character | Episodes |
|---|---|---|
| Jim Cummings | Dr. Julian Robotnik (voice) | 26 |
| Jaleel White | Sonic the Hedgehog (voice) | 26 |
| Rob Paulsen | Antoine 'Ant' Depardieu (voice) | 26 |
| Kath Soucie | Princess Sally Acorn (voice) | 26 |
| Christine Cavanaugh | Bunnie Rabbot (voice) | 26 |
| Charlie Adler | Snively (voice) | 26 |
| Bradley Pierce | Miles 'Tails' Prower (voice) | 26 |
| Cree Summer | Dulcy (voice) | 13 |
| Mark Ballou | Rotor (voice) | 13 |
| William Windom | Uncle Chuck (voice) | 10 |
| Tim Curry | King Acorn (voice) | 3 |
| Dorian Harewood | 3 | |
| Tahj Mowry | 2 | |
| Dana Hill | 2 | |
| Tim Curry | King Acorn / Keeper of the Time Stones (voice) | 1 |
| Dan Castellaneta | Lazaar (voice) | 1 |
| Michael Bell | 1 | |
| Shari Belafonte | Lupe (voice) | 1 |
| Frank Welker | Cluck / Muttski / Kraken / Swat-bots (voice) | 0 |
| Jack Angel | 0 | |
| Michael Bell | Naugus (voice) | 0 |
| Charlie Schlatter | Griff (voice) | 0 |
| Tahj Mowry | Young Sonic (voice) | 0 |
| Garry Chalk | 0 | |
| John Kassir | 0 | |
| Dorian Harewood | Ari (voice) | 0 |
| Alaina Reed Hall | 0 |