| Name | Character | Episodes |
|---|---|---|
| Benjamin Bratt | Eduardo Cruz | 14 |
| Dennis Franz | Lt. Stan Krieger | 14 |
| Don Franklin | Alex Wheeler | 14 |
| Nia Peeples | Serena Cruz | 14 |
| James Pax | Jimmy Kee | 14 |
| Craig Hurley | Danny Larsen | 14 |
| Cuba Gooding Jr. | Poptop | 3 |
| Melissa Leo | Katie Morrissey | 2 |
| Clarence Williams III | John Culver | 2 |
| William Shockley | Milt Jackson | 2 |
| James Lew | Fighter / Karate class fighter (uncredited) | 2 |
| Vincent Guastaferro | Joshua Dumars | 2 |
| Whip Hubley | Mike Morrissey | 2 |
| William Russ | Ben Farlow | 2 |
| Thomas Mikal Ford | Payday | 2 |
| Will Patton | Batiste | 1 |
| James Hong | Oscar | 1 |
| Victoria Dillard | Nicole Stanhope | 1 |
| Tobin Bell | Finley | 1 |
| Jim Beaver | Wetstone | 1 |
| Glenn Plummer | Russ Stanhope | 1 |
| Finn Carter | Lynn Ulrich | 1 |
| Richard Riehle | Gardner | 1 |
| Marc Alaimo | Major Clemens | 1 |
| France Nuyen | Ruth | 1 |
| Michael J. Pollard | 1 | |
| Tracey Walter | 1 | |
| Lorraine Toussaint | Dr. Chanel Cory | 1 |
| Lloyd Kino | Willy Leong | 1 |
| Cary-Hiroyuki Tagawa | Max | 1 |
| Billy Barty | 1 | |
| Terry Kiser | Boris Diamond | 1 |
| Steve Rankin | Kaufman | 1 |
| Charles Frank | Chuck Bradshaw | 1 |
| Stephen Davies | Ricardo MacGregor | 1 |
| Ramy Zada | Andrew Carillo | 1 |
| Michael Bofshever | 1 | |
| Pat Corley | Wayne Trilling | 1 |
| Fran Bennett | 1 | |
| Ping Wu | Johnny Chung | 1 |
| Patrick Massett | Eddie Marco | 1 |
| Pamela Dunlap | Midwife | 1 |
| Deke Anderson | Steve Michaels | 1 |
| Steven Ho | Sammy | 1 |
| Ginger Baker | Wetstone's Henchman | 1 |