| Name | Character | Episodes |
|---|---|---|
| June Allyson | Self - Host | 57 |
| James Coburn | Floyd | 1 |
| Ned Glass | Harry Vogeler | 1 |
| Joan Banks | June | 1 |
| Molly Dodd | May | 1 |
| Stephen Talbot | Ronnie Kramer | 1 |
| Dolores Hart | Elaine | 1 |
| Don Keefer | The Doctor | 1 |
| James Philbrook | Man | 1 |
| Robert Gist | Lennie | 1 |
| Lee J. Cobb | Captain Maximillian Gault | 1 |
| Ron Howard | Wim | 1 |
| Orson Bean | John Monroe | 1 |
| Kevin McCarthy | John Tourell | 1 |
| Carolyn Jones | Lena Murchak | 1 |
| Dean Stockwell | Johnny Perry | 1 |
| Debra Paget | Eve Barnes | 1 |
| Ralph Bellamy | Willard Mitchell | 1 |
| Robert Culp | Stuart Douglas | 1 |
| Akim Tamiroff | Tony | 1 |
| David Niven | Marcus Dodds | 1 |
| Susan Oliver | Judy | 1 |
| Lee Van Cleef | Peak | 1 |
| Dan O'Herlihy | David | 1 |
| James Best | Jovan Wilanskov | 1 |
| Virginia Gregg | Dorothy | 1 |
| Joseph Cotten | Dick Burlingame | 1 |
| Joseph Cotten | Charles Lawrence | 1 |
| Van Johnson | Joe Robertson | 1 |
| Bethel Leslie | Ann Royce | 1 |
| Ellen Corby | Mrs. Walters | 1 |
| J. Pat O'Malley | Judge | 1 |
| Lloyd Bridges | Capt. Anderson | 1 |
| James Gregory | John Kramer | 1 |
| Ronald Reagan | Alan Royce | 1 |
| Barry Sullivan | Richard Bradley | 1 |
| Paul Fix | Dr. Abel | 1 |
| Robert Vaughn | Dr. Guy Collins | 1 |
| Chuck Connors | George Ainsworth | 1 |
| Dick Powell | Paul Martin | 1 |
| Dick Powell | Dr. Timothy McVey | 1 |
| Leif Erickson | Andrew Middleton | 1 |
| Michael Fox | Harvey | 1 |
| Jean Willes | Tory | 1 |
| Pat Crowley | Sylvia | 1 |
| John Banner | Mr. Popper | 1 |
| Dabbs Greer | Dr. Meeker | 1 |
| John Abbott | Professor Brent | 1 |
| Anne Baxter | Louise | 1 |
| Phyllis Coates | Penny | 1 |
| Don Rickles | Announcer | 1 |
| Don Rickles | Newscaster | 1 |
| Don Rickles | Reporter | 1 |
| Stephen McNally | Jim | 1 |
| Jeff Donnell | Millie Moon | 1 |
| Paul Carr | Gary Stevens | 1 |
| Hank Patterson | Mr. Phillips | 1 |
| Irene Dunne | Dr. Gina Kerstas | 1 |
| Sylvia Sidney | Beulah Ridges | 1 |
| Bert Freed | Lieutenant | 1 |
| Bill Walker | Washroom Attendant | 1 |
| Pippa Scott | Sally Ainsworth | 1 |
| Ruth Hussey | Maia | 1 |
| Al Ruscio | Guiseppe | 1 |
| Eileen Ryan | Miss Spencer | 1 |
| Lurene Tuttle | Lillian | 1 |
| Rebecca Welles | Polly | 1 |
| Stanley Adams | Morris | 1 |
| Dick York | Lt. James Whitney | 1 |
| Steve Brodie | Sgt. Lederman | 1 |
| Harpo Marx | Benson | 1 |
| Celia Lovsky | Mrs. Franiczeck | 1 |
| Celia Lovsky | Nurse Schmidt | 1 |
| Patricia Huston | Julie Skylar | 1 |
| Barry Gordon | Pepe | 1 |
| Charles Lane | Dr. Shelley | 1 |
| Frank Lovejoy | Dave | 1 |
| Edgar Bergen | Charlie | 1 |
| Sue Randall | Ellen Monroe | 1 |
| Jane Powell | Lois Walters | 1 |
| Mona Freeman | Sandra McAllen | 1 |
| K.T. Stevens | Lorraine | 1 |
| Ann Sothern | Martha | 1 |
| Felicia Farr | Sally Anderson | 1 |
| Malcolm Atterbury | Ira Stevens | 1 |
| Bette Davis | Sarah Whitney | 1 |
| William Schallert | Lt. Barnes | 1 |
| Keenan Wynn | T. J. | 1 |
| Lawrence Dobkin | Kurt Reynolds | 1 |
| James Mason | Henry Chambers | 1 |
| Margaret O'Brien | Jean | 1 |
| Virginia Grey | Connie Vaccarous | 1 |
| Yvonne Craig | Annie | 1 |
| Edward Binns | Colonel Baldwin | 1 |
| Lyle Bettger | Phil Ross | 1 |
| Whit Bissell | Henry | 1 |
| Rossano Brazzi | Julio Vaccarous | 1 |
| Rossano Brazzi | Vittorio | 1 |
| Richard Bakalyan | Lieutenant | 1 |
| Mark Goddard | Norman | 1 |
| Steve Forrest | Major Anderson | 1 |
| Adolphe Menjou | Fitch | 1 |
| Vaughn Taylor | Artie Quint | 1 |
| Pat Carroll | Cherry | 1 |
| Steve Allen | Dr. Ben Ellison | 1 |
| Hans Conried | David Brent | 1 |
| Anne Helm | Linda Moon | 1 |
| Les Tremayne | Vance | 1 |
| Naomi Stevens | Edna Vogeler | 1 |
| Naomi Stevens | Mrs. Rose | 1 |
| Brian Donlevy | John Ridges | 1 |
| James Franciscus | Tom Grover | 1 |
| Sandy Descher | Whitney Craig | 1 |
| Irene Hervey | Gladys Anderson | 1 |
| Myrna Loy | Mary Sidney | 1 |
| Robert Horton | Danny Barnes | 1 |
| Chubby Johnson | Robey | 1 |
| Ernest Truex | Daniel | 1 |
| Alvy Moore | Cab Driver | 1 |
| Ann Blyth | Martha | 1 |
| Eduard Franz | Jules Silberg | 1 |
| Lew Ayres | Howard Moon | 1 |
| Henry Beckman | Policeman | 1 |
| Henry Beckman | Officer | 1 |
| Dick Shawn | Charlie Wilson | 1 |
| Herb Vigran | Art (uncredited) | 1 |
| Dewey Martin | Wes McAllen | 1 |
| Harry Townes | Falk | 1 |
| Harry Townes | Rudolph Miller | 1 |
| Regis Toomey | Dr. Harry Randolph | 1 |
| Wesley Lau | Joseph Dunne | 1 |
| John Hubbard | Bill | 1 |
| David White | Rolph | 1 |
| David White | Mr. Wells | 1 |
| Sean McClory | Father Ray | 1 |
| Ginger Rogers | Kay Neilson | 1 |
| Russell Johnson | Hugh | 1 |
| Russell Johnson | Tom Richards | 1 |
| Rhys Williams | Dr. Maynard Russell | 1 |
| Peter Mark Richman | David | 1 |
| Stafford Repp | Jesse | 1 |
| Jean Hagen | Elizabeth | 1 |
| Virginia Christine | Mother | 1 |
| Vic Damone | Stan Skylar | 1 |
| Al Freeman Jr. | Taxi Man | 1 |
| Howard Petrie | Dr. Abbott | 1 |
| Ann Harding | Naomi | 1 |
| Patricia Breslin | Anne Mitchell | 1 |
| Shepperd Strudwick | Stanley Sidney | 1 |
| James Burke | Policeman | 1 |
| Juanita Moore | Rosanna Watkins | 1 |
| Edna Holland | Lizzie | 1 |
| Joe Maross | Howard Cate | 1 |
| Nora Marlowe | The Nurse | 1 |
| Joseph Mell | Sam | 1 |
| Naura Hayden | Elsie | 1 |
| Jack Mullaney | Jerry | 1 |
| Jack Mullaney | Philip Roberts | 1 |
| Eugenie Leontovich | Maria Louise | 1 |
| John Alvin | Photographer | 1 |
| Douglass Dumbrille | Warden | 1 |
| Roxanne Arlen | Bobbi Gilbert | 1 |
| Donald Foster | Father Ryan | 1 |
| Darryl Hickman | Donald | 1 |
| Lyle Talbot | Mr. Anders | 1 |
| Gerald Mohr | Lt. Killian | 1 |
| Gerald Mohr | Danny Roberts | 1 |
| Sara Haden | Mother Superior | 1 |
| James Komack | Dr. James Franklin | 1 |
| Larry Thor | Physicist | 1 |