| Four old friends from high school find themselves at that stage where they realize that their lives didn't turn out exactly the way they'd planned. Over the course of one crazy evening, a series of calamities reunites this hapless brood at Los Angeles Westside Hospital, where they all find themselves under the care of a reluctant Dr. Joanna. |
| Name | Character | Episodes |
|---|---|---|
| David Arquette | Jason Ventress | 13 |
| Kelly Hu | Kelly Lee | 13 |
| Lori Loughlin | Dr. Joanna Lupone | 13 |
| Greg Germann | Sherman Yablonsky | 13 |
| Jonathan Silverman | Harry Kennison | 13 |
| Jackson Bond | Dylan Kennison | 13 |
| Leigh-Allyn Baker | 5 | |
| Natsuko Ohama | 4 | |
| Jane Seymour | 3 | |
| David Carradine | Guru Danny | 1 |
| James Hong | 1 | |
| Charlie Dell | 1 | |
| Greg Cromer | 1 | |
| Loren Lester | 1 | |
| Amy Hill | 1 | |
| Michael Kostroff | 1 | |
| Brad Grunberg | 1 | |
| Keone Young | 1 | |
| Penny Balfour | 1 | |
| E.E. Bell | 1 | |
| Sara Erikson | 1 | |
| Nayo Wallace | Pink Thong Girl | 1 |
| Ellen Albertini Dow | 1 | |
| Sterling Beaumon | 1 |