| Name | Character | Episodes |
|---|---|---|
| David Dimbleby | Self - Chair | 917 |
| Piers Morgan | Self - Panellist | 28 |
| Nicola Sturgeon | Self - Panellist | 16 |
| Ian Hislop | Self - Panellist | 14 |
| Janet Street-Porter | Self - Panellist | 14 |
| Germaine Greer | Self - Panellist | 14 |
| Will Self | Self - Panellist | 11 |
| Camilla Tominey | Self - Panellist | 11 |
| Alastair Campbell | Self - Panellist | 10 |
| David Starkey | Self - Panellist | 10 |
| John Prescott | Self - Panellist | 9 |
| Michael Portillo | Self - Panellist | 8 |
| Nadine Dorries | Self - Panellist | 7 |
| Dominic Raab | Self - Panellist | 7 |
| Benjamin Zephaniah | Self - Panellist | 7 |
| Boris Johnson | Self - Panellist | 7 |
| Geoff Norcott | Self - Panellist | 6 |
| Val McDermid | Self - Panellist | 6 |
| Billy Bragg | Self - Panellist | 6 |
| Brian Cox | Self - Panellist | 5 |
| Robert Winston | Self - Panellist | 5 |
| Ann Widdecombe | Self - Panellist | 5 |
| Jeremy Corbyn | Self - Panellist | 5 |
| Norman Tebbit | Self - Panellist | 5 |
| Simon Schama | Self - Panellist | 5 |
| Mary Beard | Self - Panellist | 5 |
| Armando Iannucci | Self - Panellist | 4 |
| Shaparak Khorsandi | Self - Panellist | 4 |
| Victoria Coren Mitchell | Self - Panellist | 4 |
| Ken Loach | Self - Panellist | 3 |
| John Sergeant | Self - Panellist | 3 |
| Julian Fellowes | Self - Panellist | 3 |
| Clive James | Self - Panellist | 3 |
| David Mitchell | Self - Panellist | 3 |
| Richard Branson | Self - Panellist | 3 |
| Tony Blair | Self - Panellist | 3 |
| Nick Clegg | Self - Panellist | 3 |
| Richard Madeley | Self - Panellist | 3 |
| Tariq Ali | Self - Panellist | 3 |
| Richard Coles | Self - Panellist | 3 |
| Griff Rhys Jones | Self - Panellist | 2 |
| Charlotte Church | Self - Panellist | 2 |
| Antony Worrall Thompson | Self - Panellist | 2 |
| Rosie Jones | Self - Panellist | 2 |
| Jo Brand | Self - Panellist | 2 |
| Steve Coogan | Self - Panellist | 2 |
| Russell Brand | Self - Panellist | 2 |
| Jerry Springer | Self - Panellist | 2 |
| Tony Robinson | Self - Panellist | 2 |
| Will Young | Self - Panellist | 2 |
| Tracy Brabin | Self - Panellist | 2 |
| Jordan B. Peterson | Self - Panellist | 2 |
| Marcus Brigstocke | Self - Panellist | 2 |
| Anthony Horowitz | Self - Panellist | 2 |
| David Cameron | Self - Panellist | 2 |
| Katie Hopkins | Self - Panellist | 2 |
| Mark Steel | Self - Panellist | 2 |
| Amol Rajan | Self - Panellist | 2 |
| Michael Winner | Self - Panellist | 2 |
| Xand van Tulleken | Self - Panellist | 2 |
| Hugh Grant | Himself - Panellist | 1 |
| Tom Conti | Self - Panellist | 1 |
| John Rhys-Davies | Self - Panellist | 1 |
| Alan Cumming | Self - Panellist | 1 |
| Alex James | Himself - Panellist | 1 |
| Ed Koch | Himself - Panellist | 1 |
| Ben Elton | Self - Panellist | 1 |
| Rose McGowan | Self - Panellist | 1 |
| David Hayman | Himself - Panellist | 1 |
| Eddie Izzard | Self - Panellist | 1 |
| Adam Pearson | Self - Panellist | 1 |
| Omid Djalili | Himself - Panellist | 1 |
| Jack Thorne | Self - Panellist | 1 |
| Rob Delaney | Self - Panellist | 1 |
| Simon Callow | Himself - Panellist | 1 |
| Laurence Fox | Self - Panellist | 1 |
| Jeremy Clarkson | Himself - Panellist | 1 |
| Mick Hucknall | Himself - Panellist | 1 |
| Zoe Lyons | Self - Panellist | 1 |
| Alexei Sayle | Himself - Panellist | 1 |
| Jonathan Lynn | Himself - Panellist | 1 |
| Brian May | Self - Panellist | 1 |
| Ed Byrne | Self - Panellist | 1 |
| Frank Skinner | Self - Panellist | 1 |
| Paddy McGuinness | Self - Panellist | 1 |
| Boy George | Self - Panellist | 1 |
| Hannah Fry | Self - Panellist | 1 |
| John Sessions | Self - Panellist | 1 |
| Harry Enfield | Self - Panellist | 1 |
| Ruby Wax | Self - Panellist | 1 |
| Jed Mercurio | Self - Panellist | 1 |
| Michael Bloomberg | Self - Panellist | 1 |
| Carol Vorderman | Herself - Panellist | 1 |
| Romesh Ranganathan | Self - Panellist | 1 |
| John Lydon | Self - Panellist | 1 |
| Rakie Ayola | Self - Panellist | 1 |
| Jeffrey Archer | Self - Panellist | 1 |
| Simon Sebag-Montefiore | Himself - Panellist | 1 |
| Jim Davidson | Self - Panellist | 1 |
| John Mortimer | Self - Panellist | 1 |
| Brian Eno | Self - Panellist | 1 |
| John O'Farrell | Himself - Panellist | 1 |
| Bianca Jagger | Herself - Panellist | 1 |
| Sandi Toksvig | Herself - Panellist | 1 |
| Victoria Derbyshire | Self - Guest Chair | 1 |
| David Baddiel | Self - Panellist | 1 |
| Hugh Fearnley-Whittingstall | Self - Panellist | 1 |
| Sue Lawley | Self - Guest Chair | 1 |
| Christopher Hitchens | Self - Panellist | 1 |
| Phil Redmond | Himself - Panellist | 1 |
| Glenda Jackson | Self - Panellist | 1 |
| Irvine Welsh | Self - Panellist | 1 |
| Nina Myskow | Self - Panellist | 1 |
| Dustin Lance Black | Himself - Panellist | 1 |
| Nick Griffin | Self - Panellist | 1 |
| David Frum | Self - Panellist | 1 |
| Rageh Omaar | Self - Panellist | 1 |
| Peter Tatchell | Himself - Panellist | 1 |
| Anthony Scaramucci | Self - Panellist | 1 |
| Grayson Perry | Self - Panellist | 1 |
| Tom Kerridge | Self - Panellist | 1 |
| Jermaine Jenas | Himself - Panellist | 1 |
| Frank Luntz | Self - Panellist | 1 |
| Edna O'Brien | Herself - Panellist | 1 |
| Mariella Frostrup | Self - Panellist | 1 |
| Dan Snow | Self - Panellist | 1 |
| Nicci Gerrard | Herself - Panellist | 1 |
| Michael Meacher | Self - Panellist | 1 |
| Andy Parsons | Himself - Panellist | 1 |
| Philippa Gregory | Self - Panellist | 1 |