| Name | Character | Episodes |
|---|---|---|
| Vanna White | Self - Co-Host | 47 |
| Pat Sajak | Self - Host | 47 |
| Krysten Ritter | Self - Contestant | 1 |
| Haley Joel Osment | Self - Contestant | 1 |
| Jack Black | Self - Contestant | 1 |
| Michelle Trachtenberg | Self - Contestant | 1 |
| Michael Rapaport | Self - Contestant | 1 |
| Snoop Dogg | Self - Contestant | 1 |
| Luis Guzmán | Self - Contestant | 1 |
| Lacey Chabert | Self - Contestant | 1 |
| Kristen Schaal | Self - Contestant | 1 |
| Julie Bowen | Self - Contestant | 1 |
| Gabriel Iglesias | Self - Contestant | 1 |
| Jason Alexander | Self - Contestant | 1 |
| Teri Hatcher | Self - Contestant | 1 |
| Kal Penn | Self - Contestant | 1 |
| Jaime Camil | Self - Contestant | 1 |
| Kevin McKidd | Self - Contestant | 1 |
| Chandra Wilson | Self - Contestant | 1 |
| Nicole Byer | Self - Contestant | 1 |
| James Pickens Jr. | Self - Contestant | 1 |
| Anthony Anderson | Self - Contestant | 1 |
| Ali Wentworth | Self - Contestant | 1 |
| Mary Lynn Rajskub | Self - Contestant | 1 |
| Paul Reubens | Self - Contestant | 1 |
| Joel McHale | Self - Contestant | 1 |
| Rob Riggle | Self - Contestant | 1 |
| Mark Duplass | Self - Contestant | 1 |
| Jenifer Lewis | Self - Contestant | 1 |
| Brooke Burns | Self - Contestant | 1 |
| Patton Oswalt | Self - Contestant | 1 |
| Lauren Lapkus | Self - Contestant | 1 |
| Anthony Michael Hall | Self - Contestant | 1 |
| Melissa Joan Hart | Self - Contestant | 1 |
| Kevin Nealon | Self - Contestant | 1 |
| Lil Rel Howery | Self - Contestant | 1 |
| Yvette Nicole Brown | Self - Contestant | 1 |
| Mayim Bialik | Self - Contestant | 1 |
| Sheryl Lee Ralph | Self - Contestant | 1 |
| Natasha Leggero | Self - Contestant | 1 |
| Drew Carey | Self - Contestant | 1 |
| John Michael Higgins | Self - Contestant | 1 |
| Thomas Lennon | Self - Contestant | 1 |
| Marcia Cross | Self - Contestant | 1 |
| Sherri Shepherd | Self - Contestant | 1 |
| Nia Vardalos | Self - Contestant | 1 |
| Andy Richter | Self - Contestant | 1 |
| June Diane Raphael | Self - Contestant | 1 |
| Nikki Glaser | Self - Contestant | 1 |
| Kate Flannery | Self - Contestant | 1 |
| Leslie Jones | Self - Contestant | 1 |
| Sasheer Zamata | Self - Contestant | 1 |
| Penn Jillette | Self - Contestant | 1 |
| Vanilla Ice | Self - Contestant | 1 |
| Debbie Gibson | Self - Contestant | 1 |
| Jennie Garth | Self - Contestant | 1 |
| Sarah Levy | Self - Contestant | 1 |
| RuPaul | Self - Contestant | 1 |
| Paula Abdul | Self - Contestant | 1 |
| Janelle James | Self - Contestant | 1 |
| Tony Hale | Self - Contestant | 1 |
| Tig Notaro | Self - Contestant | 1 |
| Noah Mills | Self - Contestant | 1 |
| Kim Fields | Self - Contestant | 1 |
| Fortune Feimster | Self - Contestant | 1 |
| Amanda Seales | Self - Contestant | 1 |
| Francia Raísa | Self - Contestant | 1 |
| Alfonso Ribeiro | Self - Contestant | 1 |
| Raven-Symoné | Self - Contestant | 1 |
| Vivica A. Fox | Self - Contestant | 1 |
| Rachael Leigh Cook | Self - Contestant | 1 |
| Constance Zimmer | Self - Contestant | 1 |
| Laverne Cox | Self - Contestant | 1 |
| Tatyana Ali | Self - Contestant | 1 |
| Kel Mitchell | Self - Contestant | 1 |
| Tori Spelling | Self - Contestant | 1 |
| Neil deGrasse Tyson | Self - Contestant | 1 |
| Jodie Sweetin | Self - Contestant | 1 |
| Joey Fatone | Self - Contestant | 1 |
| Dionne Warwick | Self - Contestant | 1 |
| Paul Scheer | Self - Contestant | 1 |
| Amber Riley | Self - Contestant | 1 |
| Steve Agee | Self - Contestant | 1 |
| Lauren Ash | Self - Contestant | 1 |
| Brendan Hunt | Self - Contestant | 1 |
| Jeannie Mai | Self - Contestant | 1 |
| Phil Rosenthal | Self - Contestant | 1 |
| Jason Mraz | Self - Contestant | 1 |
| Mario Cantone | Self - Contestant | 1 |
| Maria Menounos | Self - Contestant | 1 |
| Ron Funches | Self - Contestant | 1 |
| Tony Hawk | Self - Contestant | 1 |
| Donny Osmond | Self - Contestant | 1 |
| Luenell | Self - Contestant | 1 |
| Lil' Jon | Self - Contestant | 1 |
| Chris Perfetti | Self - Contestant | 1 |
| Chrissy Metz | Self - Contestant | 1 |
| Jim Jefferies | Self - Contestant | 1 |
| Tara Lipinski | Self - Contestant | 1 |
| Roy Wood Jr. | Self - Contestant | 1 |
| Joe Buck | Self - Contestant | 1 |
| Jeff Ross | Self - Contestant | 1 |
| Loni Love | Self - Contestant | 1 |
| Robin Thede | Self - Contestant | 1 |
| Gayle King | Self - Contestant | 1 |
| Shawn Stockman | Self - Contestant | 1 |
| Johnny Weir | Self - Contestant | 1 |
| Chance the Rapper | Self - Contestant | 1 |
| Austin Watson | Self - Contestant | 1 |
| London Hughes | Self - Contestant | 1 |
| Matt Rogers | Self - Contestant | 1 |
| Tiki Barber | Self - Contestant | 1 |
| Chris Harrison | Self - Contestant | 1 |
| Bobby Berk | Self - Contestant | 1 |
| Joel Madden | Self - Contestant | 1 |
| Karl-Anthony Towns | Self - Contestant | 1 |
| Ego Nwodim | Self - Contestant | 1 |
| Tituss Burgess | Self - Contestant | 1 |
| Melissa Villaseñor | Self - Contestant | 1 |
| Ken Jennings | Self - Contestant | 1 |
| Caroline Rhea | Self - Contestant | 1 |
| Wanya Morris | Self - Contestant | 1 |